MSAA (Methane Sulfonic Acid Anhydrous)
Discover the Product range Sulfonyls.
CAS 75-75-2
Product overview
Methane Sulfonic Acid Anhydrous (MSAA - CH3SO3H) is a strong organic acid widely used in the pharmaceutical industry due to its high acidity and high miscibility in aqueous and most organic media.
Geographic availability
- Worldwide
Chemical name : Anhydrous methane sulfonic acid, Methansulfonsäure wasser, Acide methane sulfonique anhydre
Common name : AMSA
Common name : AMSA
Properties of MSAA
Arkema manufactures MSAA in a dedicated production unit in southwest France, and produces by drying 70% methane sulfonic acid.
Arkema has developed specific process conditions to achieve high quality MSSA:
- Strong acid (pKa -1.92)
- Biodegradable
- Molecular weight 96.1
- Water content < 5000 ppm
- Residual Mesylates:
- MMS and EMS < 2 ppm
- IMS < 10 ppm
- Sulfonyl chloride < 10 ppm
Our plant is certified under ISO 9001, ISO 14001, and OHSAS.
Arkema offers global distribution of AMSA in 30, 200, 1000 liter drums and in bulk.
Benefits of MSAA
- Enhanced water solubility and stability of the active Pharmaceutical Ingredient salts
- Facilitated and faster reactions
- Lower toxicity and eco-toxicity
MSSA widely used in pharmaceutical applications
Arkema manufactures high quality Anhydrous Methane Sulfonic Acid in line with the European pharmacopeia specification. It is widely used as:
- Formation of pharmacologically acceptable API salts
- Dehydrating reaction solvent
- Reaction, extraction, purification and crystallization of synthetic intermediates synthetic raw material
- Acid catalyst, particularly for formation and removal of protecting groups