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Methane Sulfonic Acid Anhydrous (AMSA or MSAA)

Discover the Product range Sulfonyls.
Product overview

Arkema AMSA (methane sulfonic acid anhydrous - CAS 75-75-2) enjoys wide use in the pharmaceutical industry due to its high acidity and high miscibility in aqueous and most organic media. Its uses include: 




  • formation of pharmacologically acceptable API salts

  • extraction, crystallization and purification of synthetic intermediates

  • synthetic raw material

  • acid catalyst, particularly for formation and removal of protecting groups

  • dehydrating reaction solvent




AMSA is a strong organic acid (pKa-1.92). As such, it is highly corrosive in its acid form.

Geographic availability
  • Worldwide
Technical Data
Chemical name : Anhydrous methane sulfonic acid, Methansulfonsäure wasser, Acide methane sulfonique anhydre
Common name : AMSA


  • strong acid

  • biodegradable

  • molecular weight 96.1

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