Methane Sulfonic Acid Anhydrous (AMSA or MSAA)


Arkema AMSA (methane sulfonic acid anhydrous - CAS 75-75-2) enjoys wide use in the pharmaceutical industry due to its high acidity and high miscibility in aqueous and most organic media. Its uses include:


  • formation of pharmacologically acceptable API salts
  • extraction, crystallization and purification of synthetic intermediates
  • synthetic raw material
  • acid catalyst, particularly for formation and removal of protecting groups
  • dehydrating reaction solvent


AMSA is a strong organic acid (pKa-1.92). As such, it is highly corrosive in its acid form.


Are you searching for technical information? Do you need a quote? Are you looking for information on a specific event?
The Group’s experts will be pleased to assist you with any inquiry you may have.


Select the topic you are interested in: