Methane Sulfonic Acid Anhydrous (AMSA or MSAA)
Arkema AMSA (methane sulfonic acid anhydrous - CAS 75-75-2) enjoys wide use in the pharmaceutical industry due to its high acidity and high miscibility in aqueous and most organic media. Its uses include:
- formation of pharmacologically acceptable API salts
- extraction, crystallization and purification of synthetic intermediates
- synthetic raw material
- acid catalyst, particularly for formation and removal of protecting groups
- dehydrating reaction solvent
AMSA is a strong organic acid (pKa-1.92). As such, it is highly corrosive in its acid form.